Nutrition and Immunity
You are what you eat. Following that logic too far would suggest that I am a vegetarian because I eat vegetarian animals. However, as we all know, our diet does have a profound effect on our health. But how does it affect our immune systems?
First of all, most people in developed countries are not vitamin deficient. One exception to this rule is the elderly, especially single old men living alone whose idea of cooking is nuking the physical remains of yesterdays’ big mac. Another exception is iron in women of child-bearing age who lose a significant amount of this important nutrient every month due to menstration. With these exceptions in mind, most of us in developed countries get enough of almost all the good things by eating a balanced diet. And taking vitamins won’t generally help people who already have enough. An important division among vitamins, however, is between fat soluble and non fat soluble because those that are fat soluble are stored but others are not. Therefore, we need to consume non fat soluble vitamins such as vitamin C more often.
Given the fact that most of us are not deficient in most vitamins and nutrients, deficiencies in all of the following have been shown to weaken the immune system: vitamins A, B complex, C and E; Iron, protein, copper, chromium, selenium and zinc. However, it is also true that over-doses of some of these can actually suppress the immune system and cause other problems, especially fat soluble vitamins which can build up to toxic levels in some cases. Speaking of too much not being good, one of my own studies showed that too much copper (although not fat soluble) in the diet could block the enhancement of the immune system by increased chromium in the diet. The golden mean applies here. If you are in doubt as to whether you are getting too little or too much of any given nutrient, consult the recommended daily allowances published by the Food and Drug Administration (FDA).
It is hard to overdose with vitamin C since it is water soluble. It has also been shown that although this vitamin does not cure the common cold, it can, in proper doses, reduce the severity of the illness. It appears that one of the ways it might do so is by enhancing the function of certain white blood cells (leukocytes). However, even in this case, nutritionists recommend that people never take more than 1,000 milligrams per day of vitamin C since extreme amounts can cause gastrointestinal discomfort, nausea and a sudden fondness for rap music (just kidding about the rap music). It is interesting that smokers may require more vitamin C than non-smokers since they require more repair of damaged lung tissues by leukocytes.
If you want more information about the relationship between diet and immunity, I would recommend you try the PDR health web site: ( http://www.pdrhealth.com/content/nutrition_health ).
So what is the bottom line? Look at labels and other indicators of vitamins and nutrients in your diet and consult the FDA recommended levels. If you think, you might not be getting enough of any of the nutrients listed above, try a vitamin supplement or multivitamin. As long as you don’t overdose (and you won’t if you follow the FDA guidelines), you have nothing to lose but some pocket change. However, the best advice is still what your mother probably told you – eat a balanced diet that includes a varierty of fresh fruits and vegetables and you will be helping your immune system stay strong.
June 2nd, 2005 at 5:01 pm
Interesting, I have just started supplementing with plenty of vitamin C - after being a tad suspicious about most things at the health shop. I have had a huge number of colds over the last 6-8 months, and this time is my anecdotal test of Vitamin C. However I find it odd that there is a suggested limit of 1g per day — for a 100 pound sedentary old lady? - or a 200 pound man engaged in copious amounts of exercise… I suspect more is appropriate for the latter.
Haven’t noticed the overhwhelming desire for rap music (yet….
June 3rd, 2005 at 8:33 am
You make an excellent point as to the fact that what is an overdose for one might be an ideal dose for another. When it comes to medicines, my wife almost always has to reduce the dose the doctor prescribes. She is on the small side, but it I also think it has to do with metabolism. And as you suggest, size would certainly apply to vitamin doses as well.
That’s nice to hear about the lack of rap music symtoms!
Please let me know how well vitamin C works for you.
Thanks for the feedback,
June 12th, 2005 at 4:48 am
The experiment is over. Whilst I still experienced most symptoms of a cold - they never really got the better of me - although at times I was very fatigued. The only difference from previous colds was I was taking about 1-2 grams of Vit C when I felt the cold coming on.
However I’ve no doubt that I’ve got some kind of compromised immune system. Every time I increase my exercise - after about 1-3 weeks I will get sick…
June 13th, 2005 at 10:02 am
Jim,
Thanks for the update. I’m glad to hear the vitamin C helped. Your comment about excercise reminds me that ecercise and immunity is another blog I need to work on soon.
Thanks again.
June 28th, 2005 at 10:26 am
I have started supplementing with Goji juice. There are some excellent clinical studies that seem to point to immune system support with this product. I am working on overall health…taking this oversize body down to a normal size and getting in shape. I publish http://www.TheFATladyBlog.com
June 28th, 2005 at 11:10 am
Thank you very much for your comment. I think your web site is commendable. I hope your quest for improved health continues to go well and you continue to be an example for others to follow. I looked at one of the articles on an active ingredient of Goji juice ( the one published in the European Journal of Pharmacology). It is interesting that the Lycium barbarum polysaccharide-protein complex stimulates cultured leukocytes to increase their production of cytokines which stimulate other leukocytes in the immune response. I think it would be more interesting if they were able to demonstrated an increase production of cytokines in people who have consumed this substance, but the data is interesting.